(D82.4) Hyperimmunoglobulin e [ige] syndrome

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57 978 in individuals diagnosis hyperimmunoglobulin e [ige] syndrome confirmed
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2 889 deaths with diagnosis hyperimmunoglobulin e [ige] syndrome
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5% mortality rate associated with the disease hyperimmunoglobulin e [ige] syndrome

Diagnosis hyperimmunoglobulin e [ige] syndrome is diagnosed Men are 15.88% more likely than Women

33 592

Men receive the diagnosis hyperimmunoglobulin e [ige] syndrome

1 730 (5.2 %)

Died from this diagnosis.

100
95
90
85
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70
65
60
55
50
45
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15
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5
0
24 386

Women receive the diagnosis hyperimmunoglobulin e [ige] syndrome

1 159 (4.8 %)

Died from this diagnosis.

Risk Group for the Disease hyperimmunoglobulin e [ige] syndrome - Men and Women aged 5-9

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In Men diagnosis is most often set at age 0-19, 25-29, 40-44, 50-64, 70-84
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Less common in men the disease occurs at Age 20-24, 30-39, 45-49, 65-69, 85-95+Less common in women the disease occurs at Age 40-44, 50-69, 80-95+
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In Women diagnosis is most often set at age 0-39, 45-49, 70-79

Disease Features hyperimmunoglobulin e [ige] syndrome

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Absence or low individual and public risk
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Hyperimmunoglobulin e [ige] syndrome - what does this mean

Hyperimmunoglobulin e (ige) syndrome is an inherited condition caused by a mutation in the gene that encodes the protein known as signal transducer and activator of transcription 3 (stat3). this mutation results in an overproduction of ige, an antibody normally produced in response to allergies, leading to recurrent skin rashes, infections, and other symptoms.

What happens during the disease - hyperimmunoglobulin e [ige] syndrome

Hyperimmunoglobulin e (ige) syndrome is an inherited disorder characterized by elevated levels of ige antibodies in the blood, recurrent skin and lung infections, and eczema. the exact cause of this condition is currently unknown, but it is believed to be caused by a combination of genetic and environmental factors. mutations in the stat3 gene have been identified as one potential cause, leading to an impaired immune response and an inability to effectively fight off infections. additionally, environmental triggers, such as allergens, may further exacerbate the symptoms of the disorder.

Clinical Pattern

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How does a doctor diagnose

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Treatment and Medical Assistance

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8 Days of Hospitalization Required
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55 Hours Required for Outpatient Treatment

Hyperimmunoglobulin e [ige] syndrome - Prevention

The prevention of hyperimmunoglobulin e [ige] syndrome involves avoiding known triggers such as certain foods, medications, and environmental allergens, as well as controlling asthma and other allergic conditions. in addition, immunotherapy may be used to reduce the severity of allergic reactions. finally, regular monitoring of ige levels can help to identify potential flare-ups before they become severe.